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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1910 1
1976 1
1978 1
1979 2
1984 2
1985 1
1986 2
1988 1
1990 1
1991 1
1992 2
1993 5
1994 1
1995 3
1996 6
1997 2
1998 2
1999 3
2000 3
2001 7
2002 5
2003 5
2004 7
2005 5
2006 8
2007 10
2008 11
2009 13
2010 13
2011 12
2012 12
2013 12
2014 24
2015 22
2016 30
2017 27
2018 20
2019 36
2020 49
2021 53
2022 56
2023 54
2024 17

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484 results

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Page 1
Dexamethasone in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. N Engl J Med. 2021. PMID: 32678530 Free PMC article. Clinical Trial.
Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. METHODS: In this controlled, open-label trial comparing a range of possible treatments in patients who were hospitalized with Covid-19, we random …
Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death. METHODS: In …
Ezetimibe combination therapy with statin for non-alcoholic fatty liver disease: an open-label randomized controlled trial (ESSENTIAL study).
Cho Y, Rhee H, Kim YE, Lee M, Lee BW, Kang ES, Cha BS, Choi JY, Lee YH. Cho Y, et al. BMC Med. 2022 Mar 21;20(1):93. doi: 10.1186/s12916-022-02288-2. BMC Med. 2022. PMID: 35307033 Free PMC article. Clinical Trial.
BACKGROUND: The effect of ezetimibe, Niemann-Pick C1-like 1 inhibitor, on liver fat is not clearly elucidated. Our primary objective was to evaluate the efficacy of ezetimibe plus rosuvastatin versus rosuvastatin monotherapy to reduce liver fat using magnetic resonance ima …
BACKGROUND: The effect of ezetimibe, Niemann-Pick C1-like 1 inhibitor, on liver fat is not clearly elucidated. Our primary objective …
Efficacy and safety of arimoclomol in Niemann-Pick disease type C: Results from a double-blind, randomised, placebo-controlled, multinational phase 2/3 trial of a novel treatment.
Mengel E, Patterson MC, Da Riol RM, Del Toro M, Deodato F, Gautschi M, Grunewald S, Grønborg S, Harmatz P, Héron B, Maier EM, Roubertie A, Santra S, Tylki-Szymanska A, Day S, Andreasen AK, Geist MA, Havnsøe Torp Petersen N, Ingemann L, Hansen T, Blaettler T, Kirkegaard T, Í Dali C. Mengel E, et al. J Inherit Metab Dis. 2021 Nov;44(6):1463-1480. doi: 10.1002/jimd.12428. Epub 2021 Sep 7. J Inherit Metab Dis. 2021. PMID: 34418116 Free PMC article. Clinical Trial.
Niemann-Pick disease type C (NPC) is a rare, genetic, progressive neurodegenerative disorder with high unmet medical need. ...
Niemann-Pick disease type C (NPC) is a rare, genetic, progressive neurodegenerative disorder with high unmet medical need. ...
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2021 May 1;397(10285):1637-1645. doi: 10.1016/S0140-6736(21)00676-0. Lancet. 2021. PMID: 33933206 Free PMC article. Clinical Trial.
BACKGROUND: In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation. METHODS: This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 …
BACKGROUND: In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hy …
Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial.
Mateo J, Porta N, Bianchini D, McGovern U, Elliott T, Jones R, Syndikus I, Ralph C, Jain S, Varughese M, Parikh O, Crabb S, Robinson A, McLaren D, Birtle A, Tanguay J, Miranda S, Figueiredo I, Seed G, Bertan C, Flohr P, Ebbs B, Rescigno P, Fowler G, Ferreira A, Riisnaes R, Pereira R, Curcean A, Chandler R, Clarke M, Gurel B, Crespo M, Nava Rodrigues D, Sandhu S, Espinasse A, Chatfield P, Tunariu N, Yuan W, Hall E, Carreira S, de Bono JS. Mateo J, et al. Lancet Oncol. 2020 Jan;21(1):162-174. doi: 10.1016/S1470-2045(19)30684-9. Epub 2019 Dec 2. Lancet Oncol. 2020. PMID: 31806540 Free PMC article. Clinical Trial.
The TOPARP-B trial aims to prospectively validate the association between DDR gene aberrations and response to olaparib in metastatic castration-resistant prostate cancer. METHODS: In this open-label, investigator-initiated, randomised phase 2 trial following a selection ( …
The TOPARP-B trial aims to prospectively validate the association between DDR gene aberrations and response to olaparib in metastatic castra …
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2022 Jul 30;400(10349):359-368. doi: 10.1016/S0140-6736(22)01109-6. Lancet. 2022. PMID: 35908569 Free PMC article.
BACKGROUND: We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1-2 inhibitor, for the treatment of patients admitted to hospital with COVID-19. METHODS: This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOV …
BACKGROUND: We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1-2 inhibitor, for the treatment of patients admitted to hospi …
Pharmacotherapy of cerebellar and vestibular disorders.
Lemos J, Manto M. Lemos J, et al. Curr Opin Neurol. 2022 Feb 1;35(1):118-125. doi: 10.1097/WCO.0000000000001015. Curr Opin Neurol. 2022. PMID: 34845147 Review.
RECENT FINDINGS: Recently, the use of omaveloxolone for 2 years significantly improved upright stability in Friedreich's ataxia patients. In an open-label study, N-acetyl-l-leucine administered for 6-weeks significantly improved clinical impression of change, ataxia, and q …
RECENT FINDINGS: Recently, the use of omaveloxolone for 2 years significantly improved upright stability in Friedreich's ataxia patients. In …
'Species' without species.
Novick A, Doolittle WF. Novick A, et al. Stud Hist Philos Sci. 2021 Jun;87:72-80. doi: 10.1016/j.shpsa.2021.03.006. Epub 2021 Apr 2. Stud Hist Philos Sci. 2021. PMID: 34111824
We thus defend a semantic picture of the species concept as a collection of interacting patchwork structures. Thus, although not all uses of the term pick out the same kind of unit in nature, the diversity of uses reflects something more than mere polysemy. We suggest that …
We thus defend a semantic picture of the species concept as a collection of interacting patchwork structures. Thus, although not all uses of …
Low-cost, open-source XYZ nanopositioner for high-precision analytical applications.
Liao HS, Werner C, Slipets R, Emil Larsen P, Hwang IS, Chang TJ, Ulrich Danzebrink H, Huang KY, Hwu ET. Liao HS, et al. HardwareX. 2022 May 19;11:e00317. doi: 10.1016/j.ohx.2022.e00317. eCollection 2022 Apr. HardwareX. 2022. PMID: 35647417 Free PMC article.
However, the requirements of complex preload mechanism, precision machining, and precise assembly increase the cost of conventional friction-inertia nanopositioners. Herein we present the design of an open-source XYZ-axis nanopositioning system. Utilizing a magnet-based st …
However, the requirements of complex preload mechanism, precision machining, and precise assembly increase the cost of conventional friction …
Pick a side: Integrating gene expression and mechanical forces to polarize aerial organs.
Choudury SG, Husbands AY. Choudury SG, et al. Curr Opin Plant Biol. 2023 Dec;76:102460. doi: 10.1016/j.pbi.2023.102460. Epub 2023 Sep 27. Curr Opin Plant Biol. 2023. PMID: 37775406 Review.
Many of the hormone signaling pathways and genetic interactions that influence growth along these axes have been identified in the past few decades. Open questions include how and when initial gene expression patterns are set in organ primordia, and how these patterns are …
Many of the hormone signaling pathways and genetic interactions that influence growth along these axes have been identified in the past few …
484 results